Cross linking dna definition


DNA cross-linking agents, such as cisplatin derivatives (carboplatin and oxaliplatin) and mitomycin C, are especially cytotoxic to tumor cells, and their therapeutic index derives, at least in part, from the high proliferative rate of tumor cells versus normal cells. Crosslinking, also known as bioconjugation, is achieved with the use of bifunctional reagents containing reactive end groups that respond to functional groups. There are four functional groups that have been found to be successful cross-linking targets. These functional groups are primary amines, carboxyls, sulfhydryls and carbonyls. The bifunctional reagents are characterized as either ... Cross-linking agent synonyms, Cross-linking agent pronunciation, Cross-linking agent translation, English dictionary definition of Cross-linking agent. n. A chemical bond formed between adjacent chains of a complex molecule such as a polymer. Feb 24, 2009 · no its not C in the question it says "associated with cancer." and tumors are not always associated with cancer. its not b genetics test just doesn't make sense and there are too many reasons why. its not d radiation therapy has nothing to do with antibodies and antigens in the question asked it can only be 'a' chemotherapy is injection of drugs and chemicals into the body's blood, and this ...